Gamma G*B*L Butyrolactone Organic Solvents  for Steriod Powder

Quick Details:

Purity : 99.9%

CAS Registry Number

Einecs No: 202-509-5

MF: C4H6O2

MW: 86.09

Chemical Properties: Colourless oily liquid

Appearance:Colorless clear oily liquid with acetone-like odor

Uses:

(1)  G-Butyrolactone can be used to produce a-pyrrolidone, 1-Methyl-2-pyrrolidinone , polyvinyl pyrrolidone, and α-Acetyl-γ-butyrolactone, etc.

(2) G-Butyrolactone can be used as anaesthetic and tranquilizer, used to produce ciprofloxacin and interferon, as the intermediate of vitamin and rolicyprine;

(3)  G-Butyrolactone is the intermediate of plant growth stimulator and insecticide.

(4) G-Butyrolactone is a good antioxidant, plasticizer, extractant, adsorbent, dispersant, fixative and curing agent; Moreover, it can also be used in battery, capacitor and development of color film.

Product Description:

1.G-Butyrolactone (γ-butyrolactone or  G-Butyrolactone) is a hygroscopic colorless liquid with a weak characteristic odor which is soluble in water.  G-Butyrolactone is a common solvent and reagent in chemistry as well as being used as a flavouring, as a cleaning solvent, as a superglue remover, and as a solvent in some wet aluminium electrolytic capacitors. In humans it acts as a prodrug, and it is used as a recreational intoxicant with effects similar to alcohol.

2. G-Butyrolactone has been found in extracts from samples of unadulterated wines.[3] This finding indicates that  G-Butyrolactone is a naturally occurring component in some wines and may be present in similar products. The concentration detected was approximately 5 μg/mL and was easily observed using a simple extraction technique followed by GC/MS analysis.  G-Butyrolactone can be found in cheese flavourings but typically results in a content of 0.0002%  G-Butyrolactone in the final foodstuff.

3. G-Butyrolactone is a lactone. It is hydrolyzed under basic conditions, for example in a sodium hydroxide solution into sodium G-hydroxybutyrate, the sodium salt of G-hydroxybutyric acid. Under acidic conditions it forms an equilibrium mixture of both compounds. These compounds then may go on to form a polymer. When treated with a non-nucleophilic base, like lithium diisopropylamide,  G-Butyrolactone can become an alpha-carbon nucleophile. The related compound caprolactone can be used to make a polyester in this manner.

4. G-Butyrolactone is not active in its own right; its mechanism of action stems from its identity as a prodrug. The hypnotic effect of is enhanced by combination with alcohol. A 2003 rat study showed that  G-Butyrolactone in combination with ethanol showed a potentiated hypnotic effect, as the sleep-timing measure was longer than both of the individual components combined

5. G-Butyrolactone is rapidly converted into by paraoxonase (lactonase) enzymes, found in the blood.[7][8] Animals which lack these enzymes exhibit no effect from  G-Butyrolactone.[7]  G-Butyrolactone is more lipophilic (fat soluble) than, and so is absorbed faster and has higher bioavailability. Because of these pharmacokinetic differences,  G-Butyrolactone tends to be more potent and faster-acting than, but has a shorter duration; whereas the related compound 1,4-butanediol (1,4-B) tends to be slightly less potent, slower to take effect but longer-acting than.